=2) Louis Saha – 12
The Frenchman is one of three players who is joint second on our list, having hit the back of the net twelve times when facing a former club.
Like Defoe, Saha made appearances for five Premier League sides in total, across a career that spanned 14 seasons in English football.
The forward played for the likes of Newcastle United (on loan), Fulham, Manchester United, Everton and Tottenham before moving to Lazio in 2013.